An inflammasome-driven differentiation program in intestinal stem cells protects against Salmonella infection
M. Biton
Nature Immunology, Published online: 12 May 2026; doi:10.1038/s41590-026-02514-6 Salmonella-invaded intestinal stem cells activate an inflammasome-driven differentiation program toward antimicrobial Paneth cells, revealing a protective stem cell defense mechanism that helps restrict pathogen spread.