Systemic inflammation response index as an independent predictor of unfavorable prognosis and its application in risk stratification in patients with aneurysmal subarachnoid hemorrhage

Yuan-Xiang Lin
BackgroundAneurysmal subarachnoid hemorrhage (aSAH) is a devastating cerebrovascular disease associated with high rates of mortality and long-term disability. Early risk stratification is essential to guide personalized management. Systemic inflammation plays a key role in secondary brain injury after aSAH. The systemic inflammation response index (SIRI), a novel inflammatory marker combining neutrophil, monocyte, and lymphocyte counts, has shown prognostic value in multiple disorders, but its l