dominance-genetics

Nature, Published online: 15 September 2026; doi:10.1038/d41586-026-02848-z For farmers and consumers to reap the benefits, guidelines for farming gene-edited plants must be implemented with careful thought.

A massive genetic analysis of over a million people has identified hundreds of specific DNA variations tied to human personality. The findings suggest the genetic basis of personality is highly consistent and independent of a person's family environment.

HIV-1 infection begins with Env-gp120 binding to the CD4 receptor and CD4-triggered Env conformational changes that enable viral entry. To identify key Env sites that modulate Env-CD4 interactions, we analyzed growth-enhanced adaptive mutants generated through the in vitro passage of a replication-feeble HIV-1 clone carrying a CCR5-tropic env from a clinical isolate CRF08_BC. Sequencing the four …

Researchers at the University of Oslo have mapped which parts of our DNA carry the inherited differences behind complex traits and disorders.

(Nature) – AI model AlphaGenome forecasts the consequences of altering every single DNA letter in the human genome. The human genome is an easy place to get lost. Only 2% of its three billion letters encode proteins, and the rest … Read More

[Cell Death & Disease] Using transcriptome analysis of more than 15,000 RNA-seq samples across 54 human tissues, scientists identified terminal epidermal differentiation-associated RNA (TEDAR), a highly skin-enriched lncRNA.

[Communications Biology] Investigators showed that Alkbh5 expression is downregulated during late telogen, and its deletion promotes hair follicle stem cell activation and proliferation, accelerating the telogen–anagen transition in mice.

A child's genetic likelihood for attention-deficit hyperactivity disorder is associated with a higher chance of their parents divorcing. The new findings highlight how children might actively shape the life trajectories of their families.

Most salmon migrate from the sea into fresh water to spawn. This became difficult during the last Ice Age, when populations of salmon were cut off from icebound spawning grounds. A study recently published in Quaternary Research, led by fisherman-scientist Patrick Martin, used genetic analyses of more than 32,000 chum salmon to suggest that some populations survived the last Ice Age isolated in f…

Nature Communications, Published online: 14 September 2026; doi:10.1038/s41467-026-76657-3 Histone H3K36 methyltransferases are frequently altered in cancer, yet the distinct roles of H3K36 methylation states in tumorigenesis and immunity remain unclear. This study identifies an H3K36-dependent epigenetic circuit that controls endogenous retroviral elements (ERVs) repression and immune surveillan…

Nature Communications, Published online: 14 September 2026; doi:10.1038/s41467-026-77722-7 Physiological traits are modulated in response to diet. Here the authors show that RICTOR restrains host responses to vitamin B12 in C. elegans by modulating organellar quality control and regulating lifespan.

Nature, Published online: 14 September 2026; doi:10.1038/s41586-026-11124-z Encoded and non-genetic protein variants expand human functional proteome

Study results suggest how a particular genetic variant can speed onset of Huntington disease motor symptoms by up to 12.5 years and accelerate clinical measures of disease progression, by driving runaway DNA changes inside the brain's most vulnerable neurons. The post Why Does a Particular Genetic Variant Lead to Accelerated Huntington Disease Development? appeared first on GEN - Genetic Engineer…

[Nature Biotechnology] Microbial symbiosis drives the functional and phylogenomic diversification of life on Earth yet remains underexplored because of culturing challenges. This study used machine learning (ML) to predict symbiotic […] The post A Genomic Catalog Of Earth’s Bacterial And Archaeal Symbionts appeared first on Astrobiology .

Not long ago, bringing an extinct species back to life belonged to science fiction. Today, it’s the mission of a billion-dollar startup. Advances in artificial intelligence, genetics, and computational biology are changing what’s possible in conservation research, raising questions that extend far beyond the laboratory. If technology can help revive extinct species, should it? And [&#…

Nature Medicine, Published online: 14 September 2026; doi:10.1038/s41591-026-04676-0 Whole-genome sequencing of 7,851 parent–offspring families enabled the identification of parent-of-origin and post-zygotic de novo mutations that were associated with distinct procedures of assisted reproductive technology (ART), independently of parental age at conception. Increased paternal mutational burden st…

Acta Pharmacologica Sinica, Published online: 14 September 2026; doi:10.1038/s41401-026-01925-3 The RNA structural code: orchestrating gene expression and enabling precision therapies

Researchers at the University of Oslo have mapped which parts of our DNA carry the inherited differences behind complex traits and disorders. The more complex the trait, the more of those differences lie in the DNA between genes rather than in the genes themselves. This suggests that much of what shapes psychiatric and cognitive conditions lies in the parts of the genome that we understand the le…

Researchers at the University of Oslo have mapped which parts of our DNA carry the inherited differences behind complex traits and disorders. The more complex the trait, the more of those differences lie in the DNA between genes rather than in the genes themselves. This suggests that much of what shapes psychiatric and cognitive conditions lies in the parts of the genome that we understand the le…

Researchers at the University of Oslo have mapped which parts of our DNA carry the inherited differences behind complex traits and disorders. The more complex the trait, the more of those differences lie in the DNA between genes rather than in the genes themselves. This suggests that much of what shapes psychiatric and cognitive conditions lies in the parts of the genome that we understand the le…