International Journal of Drug Delivery Technology

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Background: Urinary Tract Infections (UTIs) are common bacterial infections that affect the urinary system, causing significant discomfort and potential complications if untreated. Conventional treatments often involve antibiotics, which can lead to resistance and side effects. Traditional medicine systems, like Siddha, offer alternative remedies with potentially fewer side effects. This case stu…

A stability-indicating reverse-phase high-performance liquid chromatography (RP-HPLC) method was developed and validated for the quantitative estimation of ketoconazole in bulk drug and pharmaceutical dosage forms using the Analytical Quality by Design (AQbD) framework. Critical method parameters were identified through risk assessment and optimized via Design of Experiments (DoE), ensuring robus…

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Background: Diabetic retinopathy (DR) is one of the leading microvascular complications of type 2 diabetes mellitus (T2DM) and remains a major cause of preventable vision loss worldwide. In addition to glycemic control, dyslipidemia has been implicated in the progression of retinal vascular damage. Statins, widely prescribed for lipid-lowering therapy, may provide additional protective effects ag…

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