International Journal of Drug Delivery Technology

Pemphigus is a group of relatively chronic autoimmune disorders characterized by formation of intraepithelial bullae in the skin and mucous membrane, The effect of Polarized Light therapy, expressed as pain reduction and the healing of oral cutaneous erosions in PV Objective: The aim of this study was to assess the therapeutic efficacy of Polarized Light therapy on pemphigus vulgaris patients. Pa…

Introduction: The hospital acquired Staphylococcus aureus strains are resistant to Methicillin and most of the routinely used antibiotics. Aims • To study the distribution of Methicillin Resistant Staphylococcus aureus in blood cultures. • To evaluate the antibiotic susceptibility pattern of MRSA to Vancomycin, Teicoplanin, Linezolid, Pristinamycin (Quinupristin –Dalfopristin). • To study the MIC…

Background: Immune checkpoint inhibitors (ICIs) have changed neoplastic therapy by empowering the human defense system to better recognize and eradicate neoplastic cells, in contrast to traditional treatments. They have shown notable efficacy in triple-negative breast cancer (TNBC), primarily as they target the noted proteins like PD-1, CTLA-4 and PD-L1. However, due to challenges such as immune-…

Introduction Fine Needle Aspiration Cytology (FNAC) is widely used in the evaluation of breast lesions because of its simplicity, rapidity, and cost-effectiveness. However, proliferative and atypical breast lesions often show overlapping cytomorphological features, leading to diagnostic gray zones and cytohistological discordance. The Modified Masood Scoring Index (MMSI) was introduced to improve…

The emergence of AI, blockchain, and large projects leads to the appearance of a new environment where one can develop financial literacy; nevertheless, technological adoption and financial competence have mainly been considered separately. This paper focuses on the relationship between AI engagement, blockchain engagement, technological engagement, and financial literacy under the moderating rol…

Background Pediatric cholesteatoma is an aggressive middle ear disease with high recurrence, making the choice between Canal Wall-Up (CWU) and Canal Wall-Down (CWD) surgery crucial yet controversial. Aim To evaluate clinically derived indications guiding the selection of CWU versus CWD techniques in children with cholesteatoma. Methodology A retrospective observational study was conducted on 43 p…

This study aims to examine the moderating effect of the adoption of artificial intelligence (AI) on the relationship between corporate culture, advertising strategy, competitive advantage, and the success of strategic management in small and medium-sized enterprises (SMEs) in large-scale project supply chains in the Shandong province of China. According to the research, the research model was dev…

Discharge of synthetic organic dye pollutants continues to result in irreversible damage to aquatic environments due to the rapid industrialization, growing urbanization and extensive use of non-sustainable resources. In particular, carbon-doped SnO₂ quantum dots (C-doped SnO₂ QDs) are interesting due to their visible-light photocatalytic activity, which is achieved through their nanoscale partic…

Ulcerative colitis (UC) is a chronic inflammatory bowel disease with an increasing burden in Asia. Although gut microbiota alterations have been widely reported in UC, evidence linking microbiota patterns with both clinical and endoscopic disease activity remains limited, particularly in Indonesian populations. This study aimed to evaluate the association between colonic microbiota patterns and c…

The present research work focuses on the formulation and evaluation of sustained release matrix tablets of Clopidogrel bisulfate using the melt granulation technique. The main objective of the study was to prolong drug release, enhance patient compliance, and maintain constant therapeutic levels. Clopidogrel, an antiplatelet agent with a short biological half-life, requires frequent dosing; hence…

This paper examines how the loss of biodiversity affects corporate credit ratings and the cost of debt with a particular focus given to its increasing importance as a financial risk event. A combination of financial and ESG data on 120 companies within environmentally sensitive industries were used in a mixed-method approach. It has found that a company that has a greater risk exposure to biodive…

The present study aimed to develop and characterize black seed oil-loaded microsponges for the topical management of vitiligo. Black seed oil (Nigella sativa oil), known for its antioxidant and antiinflammatory properties, was incorporated into microsponge formulations using the quasi-emulsion solvent diffusion method. Different formulations were prepared by varying polymer concentration and eval…

Neck trauma is a life-threatening emergency with high morbidity and mortality due to the involvement of vital structures such as major vessels, airway, and the aerodigestive tract. Data on neck trauma profiles in tertiary referral centers in Indonesia remain limited. This study aimed to describe the profile of neck trauma patients at Dr. Soetomo General Hospital, Surabaya, from 2019 to 2024. A de…

Background: Neck lesions include inflammatory, congenital, benign neoplastic, and malignant conditions, and early characterization guides management. Objective: To evaluate the diagnostic performance of ultrasonography in neck lesions and correlate findings with cytopathology and histopathology. Methods: This is a prospective, cross-sectional study that will be carried out in a tertiary-care teac…

Background: Impulse oscillometry can serve as a useful method in detecting initial airway changes from smoking. It is easy to use and could be good at finding small airway disease, making it something researchers are studying for use in COPD. Methods: This study, designed as a prospective comparative analysis, was conducted at a tertiary care hospital using consecutive sampling for participant re…

Financial management in large-scale energy projects is complicated by extended construction timelines, multistakeholder governance, and volatile macroeconomic conditions. Existing approaches tend to deploy artificial intelligence and financial technology as independent tools, leaving a gap in how predictive analytics can be operationally linked to financial execution. This study proposes an AI-dr…

Background The Paris System for Reporting Urinary Cytology (TPS) was introduced to improve standardization and diagnostic accuracy in urinary cytology, particularly for detection of high-grade urothelial carcinoma (HGUC). However, the indeterminate categories, namely Atypical Urothelial Cells (AUC) and Suspicious for High-Grade Urothelial Carcinoma (SHGUC), continue to represent significant diagn…

Difficult airways are a significant problem in anaesthesia, emergency medicine and intensive care with significant implications on the morbidity and mortality of the patients. The changes in the airway equipment's, visualization and algorithmic organizations have created a great difference in the clinical outcomes. The current research paper examines the current developments of difficult airway c…

Background: Diabetic retinopathy (DR) is a common complication of type 2 diabetes and a major cause of vision loss in older adults. Platelet activation contributes to damage in small blood vessels. Platelet measurements such as mean platelet volume (MPV), platelet distribution width (PDW), and platelet-large cell ratio (P-LCR) may indicate this damage. This study aimed to compare platelet measure…

This research paper examines Generation Z reaction to sustainability campaigns by influencers versus sustainability campaigns by companies. It was performed as a mixed method study combining survey data of 180 Gen Z participants with qualitative data of interviews. As indicated in the results, influencer-led campaigns do show greater scores in terms of trust (mean = 4.3) and engagement (mean = 4.…