Immunopeptidome profiling in pulmonary fibrosis provides a platform for identifying therapeutic targets
Xiawei Wei
Nature Immunology, Published online: 20 April 2026; doi:10.1038/s41590-026-02501-x Wei and colleagues characterized the MHC class I immunopeptidome in mice and humans with lung fibrosis and identified immunogenic peptides specifically expressed in fibrosis-associated lung cell subsets that blocked the progression of fibrosis in mice treated with bleomycin.