Selecting Your Plasmid Purification Kit

CoPurifying plasmid DNA from bacterial cultures is a core protocol in molecular biology. And while kit-free plasmid purification is always an option, let’s be honest — kits are quick, easy, and don’t involve phenol-chloroform. The default option is to use the kit that is already available in your lab or the one you are most familiar with. And, hey — if something is working for you, then there is no reason to change it. But what if a kit isn’t working for you, or if you don’t have an old standby.