The immobilization of glucose oxidase (GOx) in ordered mesoporous silica can provide a stable and efficient platform for glucose sensing and biocatalytic applications. This work examines a reaction-diffusion model governing glucose transport and enzymatic conversion inside GOx-loaded SBA-15 structures, with attention to both rod-shaped and cuboid particle geometries. Three coupled phenomena are incorporated into the model: intraparticle Fickian diffusion, Michaelis-Menten kinetics modified by co