Planned and ongoing searches for life, both biological and technological, confront an epistemic barrier concerning false positives – namely, that we don’t know what we don’t know. The most defensible and agnostic approach is to adopt diffuse (uninformative) priors, not only for the prevalence of life, but also for the prevalence of confounders. We evaluate […] The post The Catastrophic Consequences of Agnosticism for Life Searches and a Possible Workaroun appeared first on Astrobiology .