Clonal resolution of subpopulation heterogeneity underlying invasion and proliferation in triple-negative breast cancer
De Santiago, Carolina
dc.title: Clonal resolution of subpopulation heterogeneity underlying invasion and proliferation in triple-negative breast cancer
dc.description.abstract: Intertumoral heterogeneity is a defining hallmark of triple-negative breast cancer (TNBC), driving metastatic progression and limiting treatment response, yet the mechanisms by which distinct subpopulations arise and persist are not fully characterized. In this work, we developed and applied novel methods to interrogate clonal composition, inv