Developing a vaccine strategy to prevent the progression of pulmonary fibrosis
R. Gisli Jenkins
Nature Immunology, Published online: 20 April 2026; doi:10.1038/s41590-026-02487-6 Pulmonary fibrosis is an incurable chronic, progressive disease characterized by the emergence of fibrosis-specific cells, including a subset of fibroblasts. Proof-of-concept experiments in mice now show that the immune system can be mobilized by vaccination to target these cells and limit the development of fibrosis.