IL-9 and Blimp-1 protect the transcriptional identity of group 2 innate lymphocytes in allergic asthma
Amanda C. Poholek
Nature Immunology, Published online: 24 April 2026; doi:10.1038/s41590-026-02509-3 Poholek and colleagues show that allergic alarmin-induced IL-9 increases expression of the transcriptional repressor Blimp-1 in ILC2 cells, sustaining their cellular identity and type 2 immune responses.