mit-65d ago

Synonymous codon usage defines functional gene families

Synonymous codon usage defines functional gene families Ghanegolmohammadi, Farzan; Ohnuki, Shinsuke; Byrne, Shane; Raman, Rahul; Begley, Thomas J; Dedon, Peter C The degeneracy of the genetic code is increasingly recognized for roles in regulating translation rate, protein folding, and cell response. However, the functional genomics of codon usage patterns remains poorly defined. We previously showed that prokaryotic and eukaryotic cells respond to individual stresses by uniquely reprogramming t