Fusion Deposition Modeling (FDM) is a versatile additive manufacturing technique that enables rapid prototyping of complex geometries and supports a wide range of materials. However, FDM parts are inherently anisotropic due to their layered construction. When evaluating part feasibility, Finite Element Analysis (FEA) must accurately account for this anisotropy by creating an orthotropic material model. The mechanical properties of FDM parts are strongly influenced by slicer parameters such as extrusion temperature, layer height, and line width. Because these parameters vary across applications, it is nearly impossible to define a universal orthotropic model for any material. This project quantifies the effects of multiple slicer parameters on the ultimate tensile strength (UTS) normal to the printed layers. The UTS of FDM specimens printed with different parameter combinations will be determined using a custom-built universal tensile testing machine following ISO 527 standards. Multivariate nonlinear regression will then be applied to relate slicer parameters to UTS. The resulting mathematical model provides a predictive equation estimating tensile strength as a function of slicer parameters and material type, enabling more accurate FEA simulations and improved assessment of 3D-printed component viability.