Genomic epidemiology of the 2025 mpox epidemic in Sierra Leone
Donald S. Grant
Nature Medicine, Published online: 12 May 2026; doi:10.1038/s41591-026-04385-8 A phylogenetic analysis examined the origins of the first mpox outbreak in Sierra Leone and found evidence of an emerging lineage (G.1) that has likely descended from the Nigerian epidemic and emerged in Sierra Leone months before first detection.