A research team has developed the Coastal Water Pathogen Database (CWPD), an open-access platform that integrates metagenomic evidence on pathogenic bacteria, viruses and fungi in coastal waters with information on antibiotic resistance genes and virulence factors. Through geographic visualization, searchable records and an online annotation service, the platform allows users to examine where biological hazards occur and analyze their own sequencing data without constructing a complex bioinformatics workflow. The resource could strengthen One Health research, public-health surveillance, pandemic preparedness and the management of estuaries, aquaculture zones and other vulnerable coastal ecosystems.