A review of risk factors and intervention measures for comorbidity of diabetes and mental disorders

Globally, the increasing prevalence of diabetes and mental disorders coexisting as comorbid conditions poses significant challenges for chronic disease management. The interaction mechanisms between these two conditions involve multiple pathways, including neuroendocrine dysregulation, chronic inflammation, and neurotransmitter abnormalities. This comorbidity severely impacts patients’ health outcomes and increases clinical management complexity. Based on a narrative synthesis of relevant litera