Autologous vs. Allogeneic Cell Therapy: Key Differences in Regulatory Expectations
Shreya Yeramilli
The success of cell therapy programs depends on a clear understanding of the differences between autologous and allogeneic treatments, from their respective development challenges to the regulatory frameworks governing their clinical use. Autologous cell therapies use the patient’s own cells to create a personalized treatment with minimal risk of immune rejections. In contrast, allogeneic cell therapies utilize donor cells to develop an off-the-shelf and scalable product, however they require im