Diverse paths to broadly neutralizing antibody escape among HIV-1 strains
Theodora Hatziioannou
Nature Microbiology, Published online: 11 May 2026; doi:10.1038/s41564-026-02347-x This study shows that HIV-1 resistance to broadly neutralizing antibodies (bnAbs) in clinical development can develop easily and could compromise their use. Nevertheless, it also identifies bnAb combinations that could minimize the development of resistance.