Streptomyces produce a diphtheria toxin-like exotoxin that targets insects

Min Dong
Nature Microbiology, Published online: 30 April 2026; doi:10.1038/s41564-026-02315-5 Bioinformatic, structural and functional analyses characterize Streptomyces antiquus insecticidal protein (SAIP) as a diphtheria toxin homologue that is lethal to insect cells and targets the Flower protein as a receptor