Programmable kinetic barcoding for multiplexed RNA detection with Cas13a
Daniel A. Fletcher
Nature Biomedical Engineering, Published online: 31 March 2026; doi:10.1038/s41551-026-01642-6 A multiplexed RNA detection method exploits crRNA-dependent variability in Cas13a activity on RNA targets for kinetic barcoding and can be used to distinguish among SARS-CoV-2 variants in clinical samples.