CHAMPION-AF: When Noninferiority is Not Enough

Viktor Zarev
ACC.26 saw an overall drop in research fervor, but one long-awaited study, CHAMPION-AF, spurred a new discussion around the field of left atrial appendage closure and the data we’ve used to justify the procedure. - Left atrial appendage closure (LAAC) uses an implantable device (like Boston Scientific’s Watchman) to close off a pocket of tissue on the left atrium of the heart. - This potentially helps patients living with atrial fibrillation to minimize the risk of stroke-causing blood clots...