Pancreatic ductal adenocarcinoma (PDAC) remains one of the most biologically complex and treatment-resistant solid tumors in oncology. As researchers work to better understand tumor–stroma interactions, kinase-driven subtypes, and therapeutic vulnerabilities, traditional two-dimensional systems have shown to sometimes be insufficient. Increasingly, scientists are turning to PDAC organoids — advanced 3D cancer models derived from patient tumors The post PDAC Organoids: Advancing 3D Cancer Models