Oxidative dyslipidemia in early pregnancy: integrating atherogenic index of plasma (AIP) and uric acid (UA) to refine preeclampsia risk stratification

Preeclampsia represents an unmasking of underlying vascular and metabolic vulnerability during the physiologic stress of pregnancy. Current first-trimester screening relies heavily on body mass index which incompletely captures qualitative metabolic dysfunction, particularly in non-obese women. In this narrative perspective, we examine the atherogenic index of plasma (AIP; log10[TG/HDL-C]), which reflects triglyceride-rich lipoprotein burden and has emerged as a marker of lipid-driven vascular s