A study on the treatment of enamel white spot lesions using chitosan-calcium phosphate microgels loaded with EGCG-NPs
Donghong Yang
BackgroundDuring orthodontic treatment, fixed orthodontic appliances complicate optimal oral hygiene maintenance, frequently causing white spot lesions (WSLs). Clinically, WSLs are typical chalky-white opacities on the enamel surface, recognized as the early reversible stage of dental caries. In this study, a novel antibacterial and remineralizing material—CEN composites (Chitosan-Ca3(PO4)2, CS-CaP) microgels loaded with EGCG nanoparticles (NPs)—was designed to treat enamel white spot lesions.Me