Chemoproteomics reveals global occurrence of a phytoplankton lyase capable of reconverting progestogens

Nature Water, Published online: 05 May 2026; doi:10.1038/s44221-026-00646-5 Endocrine-disrupting progestogens pose risks to ecosystems through their biological activity. A chemoproteomics study shows that many phytoplankton species can transform these chemicals into forms that may be even more biologically active, potentially increasing ecological risk.