Jennifer E. Flythe To Co-Lead $17M PCORI Trial to Slow the Progression of Kidney Disease

Morgan Duerden
A five-year, multisite clinical trial will compare two medication strategies for advanced chronic kidney disease, enrolling 1,350 participants nationwide. Advanced chronic kidney disease (CKD) affects over 1 million people in the US. Individuals with advanced CKD have high risks of kidney failure requiring dialysis or transplantation, cardiovascular events, hospitalizations, and death, as well as a decline in quality of life. Renin-angiotensin system inhibitors (RASi) are the standard therapy fo