Analysis of mRNA and miRNA expression in RAW 264.7 macrophages infected with Salmonella enterica subsp. enterica serovar Dublin in the early stage of infection

Salmonella enterica subsp. enterica serovar Dublin (Salmonella Dublin) is a host-adapted pathogen that causes severe systemic disease in cattle and presents a zoonotic risk to humans. While macrophages play a pivotal role in host defense against Salmonella they are also an intracellular niche for bacterial persistence. However, the mechanism underlying the early transcriptional response of macrophages to Salmonella Dublin infection is poorly understood. This study used high-throughput sequencing