Polycythemia Vera: Current Therapeutic Approaches - Juniper Publishers
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Tumor Medicine & Prevention - Juniper Publishers Abstract The hemoglobin level threshold required to diagnose
PV is now established at 16.5 g/dL for men and 16 g/dL for women by the
2016 WHO classification for MPNs. The clinical course of PV might be
interrupted by thrombohemorrhagic complications and disease
transformation to MF or acute myeloid leukemia. JAK2 oncogenes
homozygosity may result in distinct tumorigenic consequences. Different
therapeutic strategies and good candidates’ pati