hematology

Aplastic anemia is a rare, life-threatening blood disorder where patients are unable to make enough blood cells due to the immune system's attack on blood stem cells. The condition can progress to myelodysplastic syndrome (MDS) and leukemia. A study led by scientists at St. Jude Children's Research Hospital, with multiple collaborating institutions, used state-of-the-art genomic techniques to pro…

Denosumab has been widely utilized in the management of osteoporosis; however, thrombocytopenia as an adverse reaction associated with denosumab has been infrequently reported, and its underlying mechanism is not yet fully understood. We present a retrospective analysis of a rare case of suspected immune-mediated thrombocytopenia resembling immune thrombocytopenia (ITP) in a patient with primary …

BackgroundThalassemia is a common disease worldwide. Oxidative stress contributes to ineffective erythropoiesis and hemolysis in β-thalassemia major (β-TM). Increasing cellular adenosine triphosphate (ATP) production by activating the activity of the pyruvate kinase (PK) may counteract oxidative stress. SNH-119014 is a novel allosteric PK activator targeting the same protein as mitapivat (AG-348)…

Scientific Reports, Published online: 22 April 2026; doi:10.1038/s41598-026-49854-9 N-WASP is downregulated in patients with acute myeloid leukemia (AML) and is associated with poor prognosis

What to do next Already submitted to Blood? Use this page to interpret the status and choose the next step. The useful next step is understanding what the status usually means at Blood, how long the wait normally runs, and when a follow-up is actually reasonable. Quick answer: Blood's review process is faster and more predictable than most top-tier journals. The ASH flagship has a lower desk reje…

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Acute lymphocytic leukaemia (ALL) is a cancer of the blood and bo…

Mofiyin Obadina, MD, and Erica Sparkenbaugh, PhD, assistant professors in the Division of Hematology and the UNC Blood Research Center, received $50,000 from NC TRaCS for their TTSA proposal entitled, “Hypoxemia-Induced Platelet Activation in Sickle Cell Disease Pregnancy: Mechanisms and Therapeutic Targets.” This award supports the development of new interdisciplinary collaborations and projects…

Northwestern Medicine scientists have uncovered key details about a group of rare but serious blood disorders, according to a study published in the Journal of Clinical Investigation. The post New Targets for Treating Blood Disorders appeared first on News Center .

In a new article in Blood, Dr. Samit Ghosh et al examine how heme could cause chronic kidney disease as well as identifying a potential protein to protect against this complication.

The American Society of Hematology has honored John Atkinson, MD, the Samuel Grant Professor of Medicine at Washington University School of Medicine in St. Louis, for his significant contributions to the field of hematology. He is one of two recipients of the Ernest Beutler Lecture and Prize and is recognized for breakthroughs that have advanced understanding […]

Jane Winter, MD, a highly regarded lymphoma expert, will serve as president of the American Society of Hematology for a year-long term through December 2022. The post Winter Elected President of the American Society of Hematology appeared first on News Center .

Tumor Medicine & Prevention - Juniper Publishers Abstract The hemoglobin level threshold required to diagnose PV is now established at 16.5 g/dL for men and 16 g/dL for women by the 2016 WHO classification for MPNs. The clinical course of PV might be interrupted by thrombohemorrhagic complications and disease transformation to MF or acute myeloid leukemia. JAK2 oncogenes homozygosity may res…

Profile of Iron Overload in Sickle Cell Syndrome Patients from Eastern India – Correlation with Common Parameters in Juniper in Open Access Blood Research & Transfusion Journal Introduction: Eastern India -the melting pot of different heterozygous Sickle cell syndrome. Mostly NTDT, we wanted to study the pattern of iron overload in this heterogeneous yet homogenous group of patients. As there is …

Bone Abnormalities in Β-Thalassemia Intermedia by Chingiz Asadov in Juniper in OABTJ β-Thalassemia intermedia (β-TI) is a clinical condition of intermediate gravity between thalassemia minor, the asymptomatic carrier, and thalassemia major, the transfusion- dependent, severe anemia . These patients do not require lifelong regular transfusions, although they may need occasional transfusions in cer…

Scientists discovered that a hemoglobin mutation was causing mild anemia in a young woman in Germany. But why did her father, who has the same mutation, not have anemia, too? The woman, who was in her 20s when diagnosed, and her father share a mutation in the gene that encodes hemoglobin, the protein in red blood cells responsible for taking up and delivering oxygen to cells around the body. The …

A small clinical trial—the first human trial of its kind—has uncovered the importance of a hormone called erythropoietin for effective umbilical cord blood transplants in leukemia and lymphoma patients. Lowering EPO levels in people aids in a process known as homing, where newly transplanted blood stem cells migrate properly to the bone marrow of the patient and begin to restore the body’s abilit…

17 July 2015 Today Paresh Vyas is Professor of Haematology and Honorary Consultant Haematologist as well as Group Leader at the MRC Molecular Haematology Unit in Oxford, UK. He runs a clinical practice in myeloid disorders (especially Acute Myeloid Leukaemia) and has research interests including haematological defect in MDS and AML, in adults and children […] The post Paresh Vyas appeared first o…

For more than fifty years, blood smear tests for sickle cell disease have been the standard diagnostic tool for physicians. But the tests, which show whether the patient’s red blood cells have an abnormal form of the iron-carrying protein hemoglobin that will cause them to take on a crescent shape in response to low oxygen levels in the blood, fails to predict the severity of symptoms. It is a la…