A method that TRACS multi-species transmission at scale

Nature Microbiology, Published online: 21 May 2026; doi:10.1038/s41564-026-02360-0 TRAnsmission Clustering of Strains (TRACS) is a versatile and highly scalable computational tool that infers strain-level transmission of microorganisms within a host population using metagenomic or single-species deep sequencing data. It accurately reveals fine-scale strain-sharing patterns and transmission networks across bacterial, viral and parasitic species.