Multinational validation of the PREVENT and SCORE2 cardiovascular risk equations across 6.4 million individuals

Jose M. Valdivielso
Nature Medicine, Published online: 05 May 2026; doi:10.1038/s41591-026-04437-z Comprehensive, multinational validation of the PREVENT and SCORE2 cardiovascular risk scores, used in the United States and Europe, respectively, in 44 observational studies and 18 randomized trials, shows similar performance for the two risk scores and generally good performance across geographical regions.