Efficacy and safety of nalbuphine vs. pethidine in oocyte retrieval: a non-inferiority, double-blinded, randomized controlled trial
Chanakarn Suebthawinkul
ObjectiveThe purpose of this study was to evaluate the efficacy and safety of Nalbuphine compared to Pethidine for pain relief during oocyte retrieval.MethodsIn a double-blinded, non-inferiority randomized controlled trial (n = 94), participants were randomized equally into two groups. The intervention group received 10 mg intravenous Nalbuphine combined with 5 mg of Midazolam, while the control group received 50 mg intravenous Pethidine with 5 mg of Midazolam. The primary outcome was pain score