Diversification in ANME-1 archaea is associated with the presence of highly variable genomic hotspots

Si Zhang
Nature Communications, Published online: 25 May 2026; doi:10.1038/s41467-026-73573-4 Anaerobic methanotrophic (ANME) archaea are abundant in marine cold seeps. Here, the authors reconstruct high-quality circular metagenomic-assembled genomes and identify variable genomic hotspots associated with phylogenomic diversity at the species and strain levels.