Researchers Identify New Kidney Pathway with Help From 1940s-Era Drug, May Improve Polycystic Kidney Disease TreatmentMayo Clinic6/16/2026Mayo Clinic researchers have identified a previously unrecognized way the kidneys regulate water balance -- an advance that could lead to improved treatments for polycystic kidney disease (PKD) and other disorders.kidneymedicinepolycystic-kidney-diseasepublic-health