The American Journal of the Medical Sciences

Paper

CAR T Cells Engineered Against LAG-3: Unleashing Potency in the Tumor Microenvironment of Breast Cancer

Mohammad A.I. Al-Hatamleh·+4 more

3/1/2026

Chimeric antigen receptor (CAR) T cell therapy has achieved remarkable success in hematologic malignancies but faces significant challenges in solid tumors such as breast cancer. A primary obstacle is the immunosuppressive tumor microenvironment (TME), which drives T-cell exhaustion and limits therapeutic efficacy. Lymphocyte-activation gene 3 (LAG-3) is a key mediator of this exhaustion, suppres…

CAR-T cell therapy researchHealth SciencesMedicineOncology

Paper

Health literacy and chronic complications of diabetes: Interpreting pathways beyond composite outcomes

Betül Erişmiş

3/1/2026

General Health ProfessionsHealth Literacy and Information AccessibilityHealth ProfessionsHealth Sciences

Paper

Prolonged QT interval is associated with 90-day mortality in sepsis independent of onset timing and heightened in male patients: A cohort study

Ya Wei·+11 more

3/1/2026

EpidemiologyHealth SciencesMedicineSepsis Diagnosis and Treatment

Paper

Hepatitis B Virus Exposure and Metabolic Dysfunction-Associated Steatotic Liver Disease in U.S. Adults: A Nationally Representative Analysis from NHANES 2017-2020

Youping Lin·...·Qiuming Lin

3/1/2026

EpidemiologyHealth SciencesLiver Disease Diagnosis and TreatmentMedicine

Paper

Outcomes of Transcatheter Aortic Valve Replacement in Patients with Rheumatologic Diseases: A Large-Scale Propensity-Matched Analysis

Olayiwola Bolaji·+8 more

3/1/2026

Cardiac Valve Diseases and TreatmentsCardiology and Cardiovascular MedicineHealth SciencesMedicine

Paper

Causal associations between gastroesophageal reflux disease and gastroduodenal ulcer: A two-sample mendelian randomisation study

Mingming Jiang·...·Weiwei Fang

3/1/2026

GastroenterologyGastroesophageal reflux and treatmentsHealth SciencesMedicine

Paper

The role and mechanisms of T cell immunity in atherosclerosis: a pathogenic and therapeutic perspective

Lai Liu·+7 more

3/1/2026

Atherosclerosis and Cardiovascular DiseasesImmunologyImmunology and MicrobiologyLife Sciences

Paper

Health literacy and its role in preventing chronic complications in diabetes: A critical review of recent findings

Muhammad Taufan Umasugi·Endah Fitriasari

3/1/2026

General Health ProfessionsHealth Literacy and Information AccessibilityHealth ProfessionsHealth Sciences

Paper

The pitfalls of conventional methods of screening for systematic reviews: Lessons learned

Mohammad Mahdi Bagheri Asl·Alejandro M Spiotta

3/1/2026

Decision SciencesMeta-analysis and systematic reviewsSocial SciencesStatistics, Probability and Uncertainty

Paper

Recurrent acute kidney injury in hospitalized adults: incidence, risk factors, and outcomes—a systematic review and meta-analysis

Shaima Ahmad AlEmam·...·Samah Fawzi Al-Shatnawi

3/1/2026

Acute Kidney Injury ResearchHealth SciencesMedicineNephrology

Paper

Early liberal fluid resuscitation increased 30-day mortality in patients post out-of-hospital cardiac arrest: A retrospective analysis of the MIMIC-IV database

Ran Han·+4 more

3/1/2026

Cardiac Arrest and ResuscitationEmergency MedicineHealth SciencesMedicine

Paper

Association of artificial intelligence derived cardiothoracic ratio assessment on non-cardiac chest CT with heart failure and all-cause mortality: A retrospective single center study

John LaForge·+11 more

3/1/2026

Cardiac Imaging and DiagnosticsHealth SciencesMedicineRadiology, Nuclear Medicine and Imaging

Paper

Current tuberculosis progress and molecular methods for identifying Mycobacterium tuberculosis

Salma Madihi·...·Mly Driss El Messaoudi

3/1/2026

Health SciencesInfectious DiseasesMedicineTuberculosis Research and Epidemiology

Paper

CRISPR-Cas9 therapy: expanding possibilities

Eli Y. Adashi

3/1/2026

Biochemistry, Genetics and Molecular BiologyCRISPR and Genetic EngineeringLife SciencesMolecular Biology

Paper

Rhino-orbito-cerebral mucormycosis in new-onset type 1 diabetes mellitus: a case-based short review

Isabella Sharifi·+6 more

3/1/2026

Antifungal resistance and susceptibilityHealth SciencesInfectious DiseasesMedicine

Paper

Telomere length and all-cause mortality risk among U.S. Adults: Examining the role of age and race/ethnicity

Hanish Kodali

3/1/2026

Health SciencesMedicinePhysiologyTelomeres, Telomerase, and Senescence

Paper

Prevalence and symptoms of post-COVID-19 syndrome in active-duty military personnel

Samantha A. Cintron·+6 more

3/1/2026

Based on the symptoms identified, finding treatments for post-COVID-19 syndrome is needed particularly for military personnel to maintain fitness and readiness.

Health SciencesLong-Term Effects of COVID-19MedicineNeurology

Paper

Macrocytes in hemochromatosis: associations of a common finding in a common disease

Robert T. Means

2/1/2026

Health SciencesHematologyHemostasis and retained surgical itemsMedicine

Paper

Incidence and prevalence of progressive pulmonary fibrosis (PPF): A systematic literature review and meta-analysis

Negar Golchin·+6 more

2/1/2026

Health SciencesInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisMedicinePulmonary and Respiratory Medicine

Paper

Changes in echocardiographic indices following kidney transplantation: A systematic review and meta-analysis

Achilleas Betsikos·+8 more

2/1/2026

Cardiology and Cardiovascular MedicineCardiovascular Function and Risk FactorsHealth SciencesMedicine

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