The Journal of Urology

Greater urine calcium reductions after thiazide treatment are observed among those with higher baseline urine calcium, and higher thiazide dose led to a larger reduction. These data are relevant for individualizing thiazide dose for kidney stone prevention.

Patients who achieved CR following UGN-102 treatment had a high probability of remaining event-free 24 months later. These data indicate UGN-102 is a novel, nonsurgical treatment that provides a durable CR for patients with recurrent LG-IR-NMIBC. Study limitations included the single-arm design and the limited racial diversity of the patients.

Pediatric patients with SB experience significantly higher antibiotic exposure, primarily driven by prolonged treatment for GU-related conditions, despite otherwise similar management of common infections. Future work will examine the patterns and necessity of such prolonged regimens.

Clinical predictors of csPCa remain similar among patients with negative mpMRI. MRI BPH and prostatitis along with lower radiologist read volume differentiated FN from TP cases. Enhanced clinical stratification tools and mpMRI refinements could improve confidence in forgoing biopsy for patients with a negative mpMRI.

Detectable ctDNA status for high-risk NMIBC pre-RC was associated with worse RFS, increased risk of pathological upstaging, and locally advanced disease with lymph node metastasis.