Preoperative ctDNA Predicts Upstaging and Recurrence in High-Risk Non-Muscle Invasive Bladder Cancer Undergoing Radical Cystectomy
Reuben BEN-DAVID·John P. Sfakianos·Sima P. Porten·Anobel Y. Odisho·Peter K. Wiklund·Carissa Chu·Igor Duquesne·Reza Mehrazin·Ahmed Eraky·Brendan L. Raizenne
Detectable ctDNA status for high-risk NMIBC pre-RC was associated with worse RFS, increased risk of pathological upstaging, and locally advanced disease with lymph node metastasis.