Chemistry - A European Journal

ABSTRACT Boron‐containing π‐conjugated molecules are promising candidates for the development of advanced Lewis‐acidic materials. Planar triphenylboranes containing heteroatoms instead of the methylene groups at the 8‐, 14‐, and 22‐positions of 1‐borahexacyclodocosanonaene are particularly interesting because they are stable in the absence of sterically protecting groups around the boron center. …

ABSTRACT Azides are widely employed in synthesis as convenient nitrene precursors, particularly in transition‐metal chemistry, where metal–nitrene intermediates enable diverse C─H amination, aziridination, and atom‐transfer processes. In stark contrast, main‐group azides, especially bismuth ones, are underrepresented and have not been fully exploited as nitrene sources. Herein, we report the synt…

ABSTRACT Estrogenic hormones are potent endocrine‐disrupting contaminants that are inefficiently removed by conventional wastewater treatment processes. Herein, we evaluate a family of isoreticular amino‐acid–derived metal–organic frameworks (MOFs), including multivariate variants, for the simultaneous capture of estrone (E1), 17β‐estradiol (E2), estriol (E3), and 17α‐ethinylestradiol (EE2) from …

ABSTRACT Steric effects strongly influence excited‐state electron transfer, yet accurately predicting their impact remains challenging. In this study, we quantified the steric bulk of 11 axial substituents on a silicon phthalocyanine photocatalyst using Sterimol parameters, and fluorescence‐quenching experiments were performed with N,N ‐diisopropylethylamine to evaluate the influence of steric ef…

ABSTRACT Rare‐earth‐based metal‐organic frameworks (RE‐MOFs) have increasly emerged as a distinctive class of functional materials for electrochemical energy storage and conversion. The unique coordination chemistry of rare‐earth ions, including high coordination numbers, shielded 4f electronic configurations, strong Lewis acidity, and accessible multivalent redox states in selected elements, end…

ABSTRACT α‐Chiral allylic amines represent a privileged structure in organic synthesis, catalysis, and other areas. Thus, the development of catalytic methods for straightforward and efficient construction of chiral allylic amines has been a longstanding interest in synthetic chemistry. In this context, transition‐metal‐catalyzed asymmetric carbon‐carbon cross‐coupling is evolving into an enablin…

ABSTRACT Self‐immolative polymers (SIPs) constitute a sophisticated class of stimuli‐responsive materials capable of undergoing complete end‐to‐end depolymerization upon a single triggering event. Among the various SIP architectures, quinone‐methide (QM)‐based poly(benzyl ether)s (PBEs) stand out owing to their high structural stability and well‐defined disassembly kinetics. This article reviews …

ABSTRACT Chemotherapy remains a major strategy for cancer treatment, with cisplatin widely used as a first‐line agent for diverse malignancies. Although cisplatin efficiently induces tumor cell death through DNA damage, its therapeutic efficacy is often limited by the development of an immunosuppressive tumor microenvironment that restricts effective immune activation. Here, we report a rationall…

ABSTRACT In this work, a series of novel unsymmetrical fluorenone derivatives bearing various head groups (H, Br, NO 2 , NH 2 , and CN) was synthesized and investigated with respect to their mesomorphic and photophysical properties. Depending on the head group, SmA, N, or SmC phases with phase widths of up to 145 K were observed, except for the NH 2 ‐substituted derivative. All mesomorphic deriva…

ABSTRACT Herein, we describe the use of IR irradiation to promote Pd‐catalyzed C(sp 3 )─H arylation and tandem C(sp 3 )─H arylation/electrophilic aromatic cyclization of ortho ‐tolualdehydes with aryl iodides via a transient directing group (TDG) strategy. The optimized conditions employ Pd(OAc) 2 (10 mol%) as the catalyst, glycine (40 mol%) as the TDG, and AgTFA (1.5 equiv.) as the additive in a…

ABSTRACT Flexible aqueous zinc‐based batteries (ZBs) are promising for wearable electronics but are hindered by low operating voltage and poor cycling stability. While zinc hexacyanoferrate (ZnHCF) represents a promising cathode candidate, its practical application is limited by rapid capacity decay. This failure is conventionally attributed to irreversible structural collapse. Herein, our findin…

ABSTRACT Electrocatalytic biomass‐based ethanol coupled with water electrolysis for hydrogen production can significantly reduce hydrogen production energy consumption while generating high‐valued acetate. However, nickel‐based non‐precious metal electrocatalysts exhibit low selectivity and stability due to imbalanced adsorption of ethanol reactants and OH − . Herein, Cu‐doped Ni(OH) 2 nanosheets…

Aggregation-induced emission luminogens (AIEgens) effectively overcome the aggregation-caused quenching (ACQ) limitations of traditional luminogens, enabling broad applications in sensing, bioimaging, radiation detection, and photovoltaic conversion. Among them, twisted intramolecular charge transfer (TICT)-type AIEgens, featuring rotatable donor-acceptor (D-A) structures, exhibit pronounced pola…

ABSTRACT G‐quadruplexes are structurally diverse nucleic acid motifs with important biological properties as well as emerging applications in biotechnology and therapeutics. Here, we investigate whether a double‐headed bis‐guanine (G) nucleotide, G G —a substantial deviation from canonical nucleic acid architecture—can be accommodated within G‐quadruplex structures and how its effects depend on s…

ABSTRACT We assess the dielectrically consistent reference interaction site model (DRISM) as an implicit electrolyte framework for modeling the electrochemical double layer, and compare it with the Poisson–Boltzmann model and explicit molecular dynamics results from the literature. We use the gold–electrolyte interface as the main test case and analyze solvent and ionic density profiles, the diff…

ABSTRACT The chiral pda derived anisole ligands L1a [ 1( R,R )] and L1b [ 1( S,S )], along with their phenol derivatives L2a [ 2( R,R )] and L2b [ 2( S,S )], were used for lanthanide‐directed synthesis of their respective Tb(III) complexes. Under thermodynamic control, the 3:1 (ligand:metal) enantiomerically pure assemblies were formed, including the Tb(III) complex of L1b ( S,S ) which was struc…

ABSTRACT Integrating microscopic catalyst design with macroscopic photophysical reaction engineering is important for improving solar‐driven CO 2 reduction. However, previous studies have largely focused on the molecular‐level optimization of catalysts, whereas the coupled effects of macroscopic reaction parameters have been less systematically investigated. This knowledge gap may limit the ratio…

Molecularly imprinted polymers have broad applications in chemistry and biology. Nanomaterials differ substantially from analogous materials on the macroscopic scale. In this work, ligand-stabilized gold nanoparticles and two micelles with different surfactant structures are used as nanoplatforms for molecular imprinting. Each platform due to its unique structure strongly impacts the imprinting, …

ABSTRACT Selective RNA cleavage could provide versatile options in therapeutic applications. In this study, multivalent RNA‐cleaving agents, featuring 1,5,9‐triazacyclododecane or guanidine groups as catalytic centers, were synthesized on a cubic octameric silsesquioxane (COSS) core. Their catalytic efficiencies were first evaluated and compared in the presence and absence of metal ions Zn 2+ , C…