Tropomyosin 3 regulates tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma to promote malignant progression in gastric cancer

BACKGROUND Tropomyosin 3 (TPM3) has been implicated in the progression of several cancers; however, its specific role and underlying molecular mechanisms in gastric cancer (GC) remain unclear. The current research aimed to investigate the role of TPM3 in the onset and advancement of GC, along with the related molecular pathways. AIM To investigate TPM3’s role in enhancing GC malignancy and elucidates the underlying molecular mechanisms. METHODS TPM3 expression in GC tissues was evaluated using b