Optimizing branch-duct intraductal papillary mucinous neoplasms surveillance: Data-driven dimensional grouping for risk stratification and cost-effectiveness
Stefano Kayali·Elisa Marabotto·A. Busatto·Federica Gaiani·Andrea Pasta·Francesco Calabrese·Stefano Fantasia·Simone Caprioli·Andrea Pierre Luzzi·C.G. De Angelis·Edoardo V Savarino·Luigi Laghi·Edoardo G. Giannini·Simone Dibitetto
BACKGROUND The rising detection of branch-duct intraductal papillary mucinous neoplasms (BD-IPMN) has led to updated surveillance guidelines, yet the true malignant transformation rate and the cost-effectiveness of these strategies remain uncertain. Current protocols are based on expert opinion rather than validated data, leading to conflicting recommendations and significant healthcare costs. This study addresses the need for an evidence-based approach to optimize surveillance by identifying ro