Single‐cell network analysis reveals gene expression programs for Arabidopsis epidermis development and metabolism

The epidermis plays essential physiological roles in plants, yet its underlying gene regulatory programs remain poorly defined. To address this gap, we integrated 11 public single-cell RNA-seq datasets of Arabidopsis shoots and leaves, extracted 30 247 epidermal cells, and constructed a single-cell gene co-expression network, AtEpidermisGGM, using the SingleCellGGM algorithm. From this network, we identified 120 co-expression modules, termed gene expression programs (GEPs), that delineate key de