Nobel Prize in Physiology/Medicine 2025: Peripheral Immune Tolerance

The immune system is one of the more complex systems of the human body, consisting of organs, such as the spleen and thymus, numerous types of cells and over 1,500 proteins. What differentiates the immune system from other systems is that it has to decide what is a foreign body and what is not – in other words, what is “self” and what is “non-self”. Attacking the Wrong Target For decades, scientists have known that this delicate balancing act can sometimes malfunction and attack the body’s own..