Cross-frequency coupling patterns during oddball processing in disorders of consciousness: a delta–gamma predominance

BackgroundPhase–amplitude coupling (PAC) between low- and high-frequency oscillations provides a candidate mechanism for integrating information across cortical networks. While PAC alterations have been reported in disorders of consciousness (DOC), the frequency specificity and task dependence of these changes remain poorly characterized.ObjectiveTo systematically examine cross-frequency coupling patterns during auditory oddball processing in DOC patients and explore whether specific frequency c