Why Impurity Analysis Matters in Oligonucleotide Quality Control In the quality control of chemically synthesized oligonucleotides, impurity analysis is a critical component for ensuring drug safety, efficacy, and consistent product quality. The industry has now reached a clear consensus on the classification of oligonucleotide impurities. In practice, these impurities are primarily categorized chemically according to their source and physicochemical properties, while their risk level is...