Brain activity, disruption and connectivity comparisons identify origins of human metacognition in other primates

Matthew FS Rushworth
Nature Human Behaviour, Published online: 18 May 2026; doi:10.1038/s41562-026-02473-w Miyamoto et al. show that human metacognition depends on multiple signals in the anterior lateral prefrontal cortex, whereas in macaques it relies on distributed processing in multiple prefrontal areas.