The role of sensory experience in the maturation of prefrontal cortical circuits

Sensory input during early life is crucial for brain circuitry to be appropriately wired and refined. Foundational studies in the past century established that early sensory input was required for the appropriate development of primary sensory areas. Further investigation in the beginning of the 21st century extended this idea by suggesting that early sensory inputs may also impact remodeling of associative cortical regions. While many of the early studies promoting this idea were based on corre