addiction

A retrospective cohort study examined recent patterns of initiating medication for alcohol use disorder (MAUD) in a national cohort of veterans hospitalized for alcohol use disorder (AUD).

Research indicates semaglutide can significantly decrease alcohol consumption and cravings in individuals with comorbid obesity and alcohol use disorder.

Alcohol use disorder is a condition that can deeply affect a person’s life. It often leads to health problems, emotional distress, and social difficulties. Around the world, it is responsible for millions of deaths each year. Although therapy and medications exist, many people still struggle to reduce their drinking, which is why researchers continue to […] The post Could a weekly injection help …

BackgroundIdentifying factors predictive of relapse in patients with alcohol use disorder (AUD) following a period of abstinence and/or treatment is essential to discover effective treatment plans for this disease. Previous evidence found that individuals with AUD who relapsed had lower sleep regularity scores than those who did not relapse. This analysis aimed to extend previous work to explore …

Alcohol use disorder is a serious health problem around the world. It affects millions of people and is linked to about 5 percent of all deaths each year. People who struggle with alcohol use may find it hard to control how much they drink, even when it causes harm to their health, relationships, and daily […] The post A weight-loss drug may help cut heavy drinking appeared first on Knowridge Sci…

ObjectiveGlucagon-like peptide-1 (GLP-1) receptor agonists have emerged as a therapeutic strategy for reducing drug craving and intake. However, their efficacy in methamphetamine use disorder remains unexplored. This study assessed the effects of repeated liraglutide treatment on methamphetamine intravenous self-administration in rats.MethodsMale Wistar rats were trained to self-administer metham…

Despite the knowledge of the health risks of smoking, exposure to nicotine leads to smoking habits. Clarifying the neuronal mechanism of smoking preference formation underlying the development of smoking habits has a great impact on the establishment of effective smoking cessation therapies. In this study, the brain regions that determine the preference for oral nicotine intake in the two-bottle …

A systematic review reveals adolescent cannabis use alters brain structure, elevates addiction risk, and impacts cognitive outcomes during critical development.

U.S. Secretary of Health and Human Services Robert F. Kennedy Jr. says a farm community in Italy for people with addiction is a model for wellness camps designed to ease the U.S. overdose crisis. Critics say the idea is dangerous.

BackgroundHarm reduction strategies for opioid use disorder (OUD) emphasize pragmatic, evidence-based approaches that reduce overdose risk, relapse, and other adverse outcomes without requiring abstinence. Medication for opioid use disorder (MOUD) and structured psychotherapy represent core harm-reduction modalities, yet their real-world comparative effectiveness, alone and in combination, remain…

People recovering from opioid addiction risk relapse when they can't get their medications after natural disasters. A group of doctors is calling for lawmakers to ease access to the meds.

Opioid use disorder during pregnancy remains a critical yet under-addressed public health issue in the U.S., according to a new study at Columbia University Mailman School of Public Health.

Alcohol addiction, also known as alcohol use disorder, is a serious and widespread mental health condition. It affects millions of people around the world and can have deep effects on physical health, emotional well-being, family life, and society. Many people think addiction is mainly about personal choice or lack of control, but modern research shows […] The post How the brain’s fear system may…

Alcohol misuse is a major global risk factor for morbidity and mortality among adolescents and young adults. During adolescence and young adulthood, alcohol can disrupt brain maturation, alter brain connectivity, and persistently weaken self-regulation. The limited effectiveness of current evidence-based treatments underscores the need for adjunctive interventions. Neuroscientific models suggest …

Troops frequently use substances to help cope with untreated PTSD and anxiety, producing a negative spiral Seven years clean, Oleksandr believed he had left addiction behind. Then, a year into fighting Russia, the Ukrainian soldier was prescribed painkillers for a shoulder injury. Under the strain of war, he relapsed and quickly began using stronger illicit opioids. “From that moment, I was fight…

A new and potentially safer opioid has been tested in lab rats, and the results suggest it relieves pain with a lower risk of addiction than other drugs in its class.

Quitting smoking is one of the most important steps a person can take to improve their health, but it is also one of the hardest. Many smokers try several times before they succeed. Over the years, different tools have been developed to help people quit, including nicotine patches, gum, counseling, and medications. Now, a new […] The post Is vaping the most effective way to help people quit smoki…

AimsA machine learning approach to identify a multidimensional signature associated with relapse and long-term outcome in alcohol dependence treatment.DesignIn this observational naturalistic study, inpatients with alcohol dependence received qualified detoxification plus CBT (Cognitive Behavioral Therapy) and were followed up 6-months after discharge to assess abstinence and drinking behavior. C…

While commonly linked to younger adults, binge drinking is a concern across all ages. Alexis LaPietra, DO, FACEP, explains how to recognize binge drinking, understand its risks, and distinguish it from alcohol use disorder. Learn how to be more mindful in social settings, build healthier habits, and access support if you're looking to cut back on alcohol.

Chronic pain is a condition that affects millions of people and can make everyday life very difficult. For many patients, the pain never truly goes away. It can feel like a constant signal in the body that cannot be switched off. Doctors often compare it to a radio that is stuck on full volume, where […] The post New therapy could turn down pain without addiction risk appeared first on Knowridge …