Neurology

This clinical trial provides Class I evidence that eptinezumab with patient education is superior to placebo with patient education in reducing MMDs in adults with CM and MOH.

This study provides Class III evidence that, in patients with SCI, HYP-CT improves average pain intensity at 6 weeks compared with UC.

The diagnostic evaluation of progressive, multifocal sensory neuropathy can be challenging and prone to misdirection without a broad differential diagnosis and a careful clinical history. We present a 41-year-old healthy man with insidious onset of right foot paresthesia, which gradually extended to his left foot and right hand over several months. This case illustrates a systematic clinical reas…

BP drops within 24 hours after successful MT are associated with worse functional outcome. Targeted measures to prevent or mitigate BP drops should be explored in future studies.

The meta-analysis found no significant association between HC use and IIH prevalence, with consistent results across various HC modalities. This evidence provides confidence to reassure patients with IIH and clinicians that the directed use of HC should be continued as appropriate. The limited quality of available evidence and considerable heterogeneity highlights the necessity for large-scale, w…

Higher BGPVS burdens are associated with higher risks of ischemic stroke and major bleeding in patients receiving antithrombotic therapy. BGPVSs may serve as useful imaging biomarkers for vascular risk assessment and personalized therapy.

These findings confirm the positive association between rest tremor amplitude and ipsilateral striatal DAT binding in a clinical sample of PD patients. However, the non-PD groups were diagnostically heterogeneous, limiting conclusions about disease specificity.

These 2 cases add to the growing evidence regarding Aβ transmissibility in humans and remove the confounding factor of neurosurgery. Iatrogenic CAA diagnosis should be considered after exclusion of genetic causes in patients with early-onset clinical and neuroimaging features of CAA. Patient should have evidence of Aβ accumulation in the CNS and a suggestive medical history. Treatments at risk sh…

In the NeuroImage "Paradoxical Ipsilateral Hemiparesis With Thrombectomy Recanalization: DTI Reveals Uncrossed Corticospinal Tract in Adult Schizencephaly" by

(INTERACT1 NCT00226096; INTERACT2 NCT00716079; INTERACT3 NCT03209258; INTERACT4 NCT03790800; ATACH-2 NCT01176565).