Naunyn-Schmiedeberg s Archives of Pharmacology

Paper
Nairana Mithieli de Queiroz Eskuarek Melo·...·Lívia Bracht
2d ago

Abstract Arsenic trioxide has recently been approved for the treatment of acute promyelocytic leukemia, but it is also a highly toxic compound. The purpose of the present work was to obtain a general view about the acute effects of arsenic trioxide on liver metabolism using the isolated perfused rat liver, a system that preserves microcirculation and cell polarity. Hepatic lactate and alanine glu…

Biochemistry, Genetics and Molecular BiologyLife SciencesMolecular BiologyRetinoids in leukemia and cellular processes
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