Trends of Urinary Calcium-creatinine Ratio during Pregnancy as an Early Predictor of Pre-eclampsia: A Prospective Cohort Study

Introduction: Hypertensive disorder in pregnancy is a major cause of maternal and perinatal morbidity and mortality worldwide. Urinary Calcium:Creatinine Ratio (CCR) has been reported as a potentially useful biomarker for predicting Preeclampsia (PE). Aim: To assess the trend of urinary CCR during pregnancy and to evaluate its association with the development of PE among antenatal women. Materials and Methods: A prospective cohort study was conducted at the Department of Obstetrics and Gynaecolo